Larvicidal activity of Citrofortunella microcarpa against Mosquito

Dengue
virus (DV) (genus Flavivirus) is a mosquito-bome well-known infection, the
causative agent of dengue fever (DF) and hemorrhagic fever (DHF). It is caused
by four distinctive serotypes of viruses namely DENV-1, DENV-2, DENV-3, and
DENV-4 come from the Flaviviridae family.
The viruses are spread through the bite of infected Aedes aegypti mosquitoes that feed throughout the day. Mostly,
these mosquitoes can be found in places with stagnant water, including water
tanks, tires, containers, and puddles. Some effects of this infection are
flu-like illness and lethal disease which is severe dengue.

            In recent years, the cases of dengue
has risen excessively around the world. An estimated 390 million dengue cases
are reported per year, 96 million shown clearly. Another report, of
frequentness of dengue, calculated 3.8 billion people, in 128 countries are in
danger because of dengue viruses. The incidence of dengue cases recounted,
elevated from 2.2 million to 3.2 million in 2010 to 2015 respectively. Although
the global encumber of infection is unstable, the installation of activities to
account initially illustrates the due accretion in the number of cases recorded
in preceding years. More than 100 countries in the WHO regions of Africa, the
America, the Eastern Mediterranean, South-East Asia and the Western Pacific
regions are facing this problem. Previously the number of recorded cases has
resumed to arise. Almost 2.3 million cases of dengue were recorded only in
America in 2015. 10 300 cases were recognize as severe dengue resulting 1180
deaths (Bhatt S, 2015).

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            Nationally,
the Philippines has declared dengue cases. Regions where mostly affected by
dengue are Central Visayas, Central Luzon, Calabarzon, Metro Manila and
Soccsksargen. Dengue happens nationally and done throughout the year in the
Philippines especially in urban and pre-urban places. Transmission of the
infection happens throughout the rainy season, May down to November (International
Association for Medical Assistance to travelers, 2016). 43, 780 cases, 250
deaths and 85 casualties were reported and recorded by the Department of
Health. Generally, there were 6,281 dengue cases in Central Visayas, 5,146 in
Central Luzon, 5,008 in Calabarzon, 5,565 in Metro Manila, and 4,863 in
Soccsksargen. There also provinces affected by dengue virus including Cebu
(12%), South Cotabato (6.4%), and Pampanga (4.7%) (The Manila Times).

Locally, there is also a number of dengue cases. According
to the annual morbidity record of Maco Main Health Center in September 2017,
there are 4 people were affected by dengue in Maco. 

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